Best Bets for NCAA Basketball Picks Against the Spread for Tuesday, January 21

Published 12:33 am Tuesday, January 21, 2025

The North Carolina Tar Heels versus the Wake Forest Demon Deacons is one of many compelling options on Tuesday in college basketball action — suggested picks against the spread for 10 games are available here.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: North Carolina +1.5 vs. Wake Forest

  • Matchup: North Carolina Tar Heels at Wake Forest Demon Deacons
  • Time: 9:00 PM ET
  • Date: January 21
  • Computer Projection: North Carolina by 4.5 points (Bet now on BetMGM)
  • Spread: Wake Forest (-1.5)
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Rhode Island +7.5 vs. VCU

  • Matchup: VCU Rams at Rhode Island Rams
  • Time: 7:00 PM ET
  • Date: January 21
  • Computer Projection: VCU by 2.5 points (Bet now on BetMGM)
  • Spread: VCU (-7.5)
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Butler +12.5 vs. UConn

  • Matchup: Butler Bulldogs at UConn Huskies
  • Time: 7:00 PM ET
  • Date: January 21
  • Computer Projection: UConn by 7.6 points (Bet now on BetMGM)
  • Spread: UConn (-12.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: UTSA +12.5 vs. UAB

  • Matchup: UTSA Roadrunners at UAB Blazers
  • Time: 7:30 PM ET
  • Date: January 21
  • Computer Projection: UAB by 9.1 points (Bet now on BetMGM)
  • Spread: UAB (-12.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Wisconsin +3.5 vs. UCLA

  • Matchup: Wisconsin Badgers at UCLA Bruins
  • Time: 9:30 PM ET
  • Date: January 21
  • Computer Projection: UCLA by 0.2 points (Bet now on BetMGM)
  • Spread: UCLA (-3.5)
  • TV Channel: Peacock

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ATS Pick: Washington +12.5 vs. Oregon

  • Matchup: Washington Huskies at Oregon Ducks
  • Time: 11:00 PM ET
  • Date: January 21
  • Computer Projection: Oregon by 9.3 points (Bet now on BetMGM)
  • Spread: Oregon (-12.5)
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Ohio State +10.5 vs. Purdue

  • Matchup: Ohio State Buckeyes at Purdue Boilermakers
  • Time: 7:30 PM ET
  • Date: January 21
  • Computer Projection: Purdue by 7.3 points (Bet now on BetMGM)
  • Spread: Purdue (-10.5)
  • TV Channel: Peacock

ATS Pick: Illinois State -7.5 vs. Indiana State

  • Matchup: Indiana State Sycamores at Illinois State Redbirds
  • Time: 8:00 PM ET
  • Date: January 21
  • Computer Projection: Illinois State by 10.5 points (Bet now on BetMGM)
  • Spread: Illinois State (-7.5)
  • TV Channel: MARQ

ATS Pick: UCF +15.5 vs. Iowa State

  • Matchup: UCF Knights at Iowa State Cyclones
  • Time: 8:00 PM ET
  • Date: January 21
  • Computer Projection: Iowa State by 12.6 points (Bet now on BetMGM)
  • Spread: Iowa State (-15.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Missouri +2.5 vs. Texas

  • Matchup: Missouri Tigers at Texas Longhorns
  • Time: 9:00 PM ET
  • Date: January 21
  • Computer Projection: Missouri by 0 points (Bet now on BetMGM)
  • Spread: Texas (-2.5)
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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