College Basketball Picks Against the Spread: ACC Games Today, January 21

Published 4:55 am Tuesday, January 21, 2025

Tuesday’s ACC college basketball schedule has lots in store. Among those games is the Louisville Cardinals taking on the SMU Mustangs, and we have picks against the spread right here for all the games.

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ACC Picks ATS Today

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Pick: Boston College +8 vs. Virginia

  • Matchup: Boston College Eagles at Virginia Cavaliers
  • Projected Favorite & Spread: Virginia by 7.4 points (Bet on BetMGM)
  • Spread: Virginia -8
  • Time: 7:00 PM ET
  • Date: January 21
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Louisville +2.5 vs. SMU

  • Matchup: Louisville Cardinals at SMU Mustangs
  • Projected Favorite & Spread: Louisville by 0.1 points (Bet on BetMGM)
  • Spread: SMU -2.5
  • Time: 9:00 PM ET
  • Date: January 21
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: North Carolina +1 vs. Wake Forest

  • Matchup: North Carolina Tar Heels at Wake Forest Demon Deacons
  • Projected Favorite & Spread: North Carolina by 4.5 points (Bet on BetMGM)
  • Spread: Wake Forest -1
  • Time: 9:00 PM ET
  • Date: January 21
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

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