Saturday’s college basketball lineup in the ACC has several top-tier games, including a matchup between the Illinois Fighting Illini and the Duke Blue Devils. Continue reading for all our predictions against the spread.

Catch tons of live college basketball, plus original programming, with ESPN+ or the Disney Bundle.

ACC Picks ATS Today

Place your bets on any men’s college basketball matchup at BetMGM. Sign up today using our link.

Pick: Florida State +13.5 vs. Louisville

• Matchup: Florida State Seminoles at Louisville Cardinals
• Projected Favorite & Spread: Louisville by 11.9 points (Bet on BetMGM)
• Spread: Louisville -13.5
• Time: 12 p.m. ET
• Date: February 22
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Wake Forest -2.5 vs. NC State

• Matchup: Wake Forest Demon Deacons at NC State Wolfpack
• Projected Favorite & Spread: Wake Forest by 3.6 points (Bet on BetMGM)
• Spread: Wake Forest -2.5
• Time: 2 p.m. ET
• Date: February 22
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Boston College +3.5 vs. Georgia Tech

• Matchup: Georgia Tech Yellow Jackets at Boston College Eagles
• Projected Favorite & Spread: Georgia Tech by 2.1 points (Bet on BetMGM)
• Spread: Georgia Tech -3.5
• Time: 2 p.m. ET
• Date: February 22
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Pittsburgh -2.5 vs. Notre Dame

• Matchup: Pittsburgh Panthers at Notre Dame Fighting Irish
• Projected Favorite & Spread: Pittsburgh by 2.8 points (Bet on BetMGM)
• Spread: Pittsburgh -2.5
• Time: 2:15 p.m. ET
• Date: February 22
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: SMU +1.5 vs. Clemson

• Matchup: Clemson Tigers at SMU Mustangs
• Projected Favorite & Spread: SMU by 1 points (Bet on BetMGM)
• Spread: Clemson -1.5
• Time: 4 p.m. ET
• Date: February 22
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Virginia Tech +2.5 vs. Miami (FL)

• Matchup: Virginia Tech Hokies at Miami Hurricanes
• Projected Favorite & Spread: Miami (FL) by 1.8 points (Bet on BetMGM)
• Spread: Miami (FL) -2.5
• Time: 6 p.m. ET
• Date: February 22
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Illinois +9.5 vs. Duke

• Matchup: Illinois Fighting Illini vs. Duke Blue Devils
• Projected Favorite & Spread: Duke by 7.4 points (Bet on BetMGM)
• Spread: Duke -9.5
• Time: 8 p.m. ET
• Date: February 22
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Stanford -5.5 vs. Cal

• Matchup: California Golden Bears at Stanford Cardinal
• Projected Favorite & Spread: Stanford by 6.6 points (Bet on BetMGM)
• Spread: Stanford -5.5
• Time: 10 p.m. ET
• Date: February 22
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.